In what should be a one-sided affair, Melbourne should make it four wins from their past five encounters against North Melbourne.
The Kangaroos have struggled in the last month after a positive opening fortnight that yielded two victories.
The Demons haven't reached their full potential as key personnel have been in and out of the team.
However, Simon Goodwin's men do sit third on the ladder and will be licking their lips at Saturday night's contest in hope they can add some percentage.
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The first bounce of the game between Melbourne and North Melbourne will be at 7:25 pm AEST, at the MCG in Melbourne.
What time is the AFL today? Melbourne vs North Melbourne start time
Saturday night's game between Melbourne and North Melbourne will begin at 7:25pm AEST.
The game will be held at the MCG in Melbourne.
| City | Sydney | Melbourne | Brisbane | Adelaide | Perth |
| Time | 7:25pm | 7:25pm | 7:25pm | 6:55pm | 5:25pm |
How to watch or livestream Melbourne vs North Melbourne
Channel 7/Fox Footy will broadcast Saturday night's game.
Coverage on Channel 7/Fox Footy will start from 7:00 pm AEST, with first bounce scheduled for 7:25 pm AEST.
7Plus/Kayo Sports will stream the game live.
| TV Channel | Channel 7/Fox Footy |
| Live stream | 7Plus/Kayo Sports |
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Melbourne vs North Melbourne odds
Melbourne are favoured to win this game, paying $1.07 to North Melbourne's $8.50 to win per BlueBet.
Melbourne vs North Melbourne round 6 team lists
Melbourne's starting 22
| Full Back | Jake Bowey | Steven May | Jake Lever |
| Half Back | Angus Brayshaw | Bayley Fritsch | Trent Rivers |
| Centre | Ed Langdon | Clayton Oliver | Tom Sparrow |
| Half Forward | Jack Viney | Josh Schache | Michael Hibberd |
| Full Forward | James Jordon | Jacob van Rooyen | Judd McVee |
| Followers | Max Gawn | Christian Petracca | Kade Chandler |
| Interchange | Brodie Grundy | Lachie Hunter | Alex Neal-Bullen |
| Kysaiah Pickett |
INS: Josh Schache
OUTS: Bailey Laurie (Sub), Harrison Petty (Injured)
North Melbournes' starting 22
| Full Back | Griffin Logue | Ben McKay | Jack Ziebell |
| Half Back | Luke McDonald | Aaron Hall | Harry Sheezel |
| Centre | Curtis Taylor | Tom Powell | Liam Shiels |
| Half Forward | Paul Curtis | Charlie Comben | Jaidyn Stephenson |
| Full Forward | Jy Simpkin | Nick Larkey | Callum Coleman-Jones |
| Followers | Todd Goldstein | Darcy Tucker | Cameron Zurhaar |
| Interchange | Aidan Corr | Ben Cunnington | Bailey Scott |
| Kayne Turner |
INS: Callum Coleman-Jones, Jy Simpkin
OUTS: Daniel Howe (Omitted), Will Phillips (Omitted), Luke Davies-Uniacke (Injured)